407-553-8587 (Call or Text) | 720 W. Princeton Street | Orlando, FL 32804

Spravato Treatment in Orlando, FL


A new path forward when depression hasn’t lifted.

  • Now accepting new patients

  • In-office treatment in College Park, Orlando

  • Supervised by experienced psychiatric providers

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If traditional antidepressants haven’t worked, you’re not out of options. Millions of people live with depression that doesn’t fully respond to medication. It doesn’t mean you’ve failed. It doesn’t mean you’re out of hope.

Spravato® (esketamine) is an FDA-approved nasal spray specifically designed for treatment-resistant depression. At Breakthrough HQ, we deliver this innovative treatment in a calm, supportive environment with continuous medical supervision — so you can feel safe, seen, and cared for at every step.


This may be the moment everything finally shifts.

You May Be a Good Candidate If…

You might benefit from Spravato if you:

  • Have tried 2 or more antidepressants without meaningful improvement

  • Feel stuck, numb, or unable to function

  • Experience side effects with traditional medications

  • Want a treatment supervised carefully in a supportive environment

  • Are navigating major depressive disorder with suicidal thoughts or actions

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What to Expect

You’ll never do this alone — we stay with you every step of treatment.

  • Number 1

    Initial Consultation

    (60 minutes)

    We begin with a comprehensive psychiatric evaluation to confirm whether Spravato is appropriate for you. Together, we’ll review your history, prior treatments, and treatment goals.

  • Number 2

    Treatment Sessions

    (2 hours each)

    Spravato treatments take place in our office under direct supervision. Each session lasts about two hours to allow for administration, monitoring, and recovery before you go home.

  • Number 3

    Ongoing Monitoring

    (30 minutes)

    We will meet for 30-minute follow-up appointments after week 1, then at the end of months 1, 2, and 3. Once you are in the maintenance phase (after month 3), follow-up frequency is determined on a case-by-case basis, guided by your response, tolerability, and clinical progress.

Why Patients Choose Breakthrough HQ for Spravato


A Calming, Stigma-Free Space

We’ve built an environment that feels warm, safe, and unhurried — so you can focus on healing.

Expert Psychiatric Providers

Our team specializes in medication management and depression treatment, with extensive experience supporting patients who haven’t found relief elsewhere.

Continuous In-Session Monitoring

Your safety is our priority. Every dose is supervised, and you’re never alone during treatment.

Whole-Person Support

We collaborate with your care team when needed and create a plan that considers your overall mental and physical wellbeing.

How Spravato Works

Traditional antidepressants work on serotonin. Spravato works differently — on the brain’s glutamate system — helping create new neural connections that can lift mood and relieve symptoms more quickly.

It is approved for:

  • Treatment-resistant depression (TRD)

  • Major depressive disorder with suicidal thoughts or actions (MDD with SI)

Spravato must be administered only in certified treatment centers, like Breakthrough HQ, with required monitoring for your safety.

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Frequently Asked Questions

  • Spravato works on a different brain pathway (the glutamate system) than standard antidepressants, which may help when other medications haven’t.

  • Treatment usually begins twice a week for four weeks, then tapers to once a week for the next four weeks. After that, sessions continue either weekly or every other week on an ongoing basis, depending on your progress.

  • Coverage varies by plan. Our team can help determine your benefits and discuss financial options.

  • Our general age range is 6 to 64. Each provider has their own specialty within that range, so not all providers see every age group. The easiest way to check is by viewing provider profiles on our booking page or by reaching out to our office, and we’ll make sure you’re scheduled with the right provider for your needs.

  • No. Because Spravato may cause temporary drowsiness or dizziness, you cannot drive until the next day. Please arrange a safe ride home after each session.

Meet the Breakthrough HQ Team

Compassionate providers who walk with you through every step of your healing.

When you’re exploring Spravato, you want more than clinical expertise — you want providers who genuinely understand what you’re going through. Our team blends evidence-based psychiatric care with uncommon warmth, deep listening, and true partnership.

  • We don’t rush appointments.

  • We don’t make assumptions.

  • We take the time to see all of you — not just your symptoms.

Our Spravato patients are cared for by a team committed to your safety, comfort, and long-term wellbeing.

  • Portrait of Lisa Babb, APRN, PMHNP-BC, FNP-BC

    Lisa Babb, APRN, PMHNP-BC, FNP-BC

    Lisa founded Breakthrough HQ to create a stigma-free space where patients feel known, supported, and cared for. While she no longer accepts new patients, she remains deeply involved in clinical oversight, patient experience, and ensuring every care pathway aligns with Breakthrough HQ’s values. Her vision guides the environment you’ll experience during your Spravato treatments — calm, attentive, and focused on your whole wellbeing.

  • Portrait of Libby Ortiz, APRN, PMHNP-BC

    Libby Ortiz, APRN, PMHNP-BC

    Known for her calm presence and thoughtful listening, Libby delivers compassionate psychiatric care for adults and adolescents. She specializes in depression treatment, ADHD evaluation, and medication management. Libby walks closely with Spravato patients throughout their treatment, offering steady support, clear communication, and a safe space to heal.

    Currently accepting patients ages 13–64

Take the First Step Toward Relief


If you’re living with depression that hasn’t improved with other treatments, Spravato may help you finally move forward.

Schedule a Consultation

Contact Us


We’re here to help.

hello@breakthroughhq.com
407-553-8587 (Call or Text)

Schedule a Consultation

720 W. Princeton Street | Orlando, FL 32804
Monday - Thursday 9 AM - 6 PM | Friday 9 AM - 5 PM

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